{"id":1008,"date":"2025-04-02T16:51:35","date_gmt":"2025-04-02T08:51:35","guid":{"rendered":"https:\/\/cvd.xin\/?p=1008"},"modified":"2025-04-07T17:28:59","modified_gmt":"2025-04-07T09:28:59","slug":"%e6%88%91%e6%89%8d28%e5%b2%81%ef%bc%8c%e8%a1%80%e8%84%82%e9%ab%98%e4%ba%86%e4%b8%a4%e5%b9%b4%ef%bc%8c%e5%8d%b4%e6%b5%91%e7%84%b6%e4%b8%8d%e7%9f%a5-cloned-218","status":"publish","type":"post","link":"https:\/\/cvd.xin\/?p=1008","title":{"rendered":"\u9884\u9632\u731d\u6b7b"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1008\" class=\"elementor elementor-1008\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d325bcd e-flex e-con-boxed e-con e-parent\" data-id=\"d325bcd\" data-element_type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div 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class=\"elementor-icon-list-item elementor-repeater-item-e244842 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/cvd.xin\/?m=20250402\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>2025-04-02<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b44001f ha-has-bg-overlay elementor-widget elementor-widget-text-editor\" data-id=\"b44001f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"letter-spacing: -0.27px;\"><b>\u4ec0\u4e48\u662f\u731d\u6b7b\uff1f<\/b><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a043a5a elementor-widget elementor-widget-text-editor\" data-id=\"a043a5a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-size: inherit; text-align: inherit; color: var( 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elementor-widget elementor-widget-text-editor\" data-id=\"4c1e361\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>\u54ea\u4e9b\u4eba\u66f4\u6613\u53d1\u751f\u731d\u6b7b\uff1f<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c68d4ff elementor-widget elementor-widget-text-editor\" data-id=\"c68d4ff\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u6bcf\u4e2a\u5e74\u9f84\u6bb5\u5747\u53ef\u53d1\u751f\u731d\u6b7b\uff0c\u4f46\u731d\u6b7b\u5df2\u7ecf\u8d8a\u6765\u8d8a\u591a\u5730\u53d1\u751f\u5728\u9752\u58ee\u5e74\u4eba\u7fa4\u4e2d\uff0c\u4fe8\u7136\u6210\u4e3a\u6211\u4eec\u4e0d\u80fd\u5ffd\u89c6\u7684\u60c5\u51b5\u3002\u9752\u5c11\u5e74\u5fc3\u6e90\u6027\u731d\u6b7b\u7684\u9996\u8981\u539f\u56e0\u4e3b\u8981\u662f\u5fc3\u808c\u75c5\uff0c\u6bd4\u5982\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff08Hypertrophic cardiomyopathy, HCM\uff09\uff0c\u6269\u5f20\u578b\u5fc3\u808c\u75c5\uff08Dilated cardiomyopathy, DCM\uff09\u7b49<sup>[1]<\/sup>\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-540d979 elementor-widget elementor-widget-image\" data-id=\"540d979\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"580\" height=\"592\" 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class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0<span style=\"font-size: 12px; text-align: center; color: #4d6940; font-family: 'PingFang SC', system-ui, -apple-system, BlinkMacSystemFont, 'Helvetica Neue', 'Hiragino Sans GB', 'Microsoft YaHei UI', 'Microsoft YaHei', Arial, sans-serif; letter-spacing: 1px;\">\u5404\u7c7b\u5fc3\u808c\u75c5\u8868\u578b\u7279\u5f81\u56fe[6]<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c9e0f3e elementor-widget elementor-widget-text-editor\" data-id=\"c9e0f3e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0<\/p><p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u5728\u4eba\u7fa4\u4e2d\uff0c\u51a0\u5fc3\u75c5\u4e0e\u8111\u5352\u4e2d\u9057\u4f20\u98ce\u9669\uff08Genetic Risk\uff09\u9ad8\u7684\uff0c\u5982\u6709\u5438\u70df\u3001\u9157\u9152\uff0c\u9ad8\u6cb9\u3001\u9ad8\u76d0\u3001\u9ad8\u7cd6\u996e\u98df\uff0c\u4e45\u5750\u3001\u7f3a\u4e4f\u8fd0\u52a8\uff0c\u4ee5\u53ca\u7ecf\u5e38\u71ac\u591c\u7b49\u4e0d\u5065\u5eb7\u7684\u751f\u6d3b\u65b9\u5f0f\u66f4\u5bb9\u6613\u5bfc\u81f4\u51a0\u72b6\u52a8\u8109\u7ca5\u6837\u786c\u5316\uff0c\u6700\u7ec8\u5bfc\u81f4\u7ed9\u5fc3\u810f\u4f9b\u8840\u7684\u51a0\u72b6\u52a8\u8109\u7a81\u53d1\u7f3a\u8840\u4e86\uff0c\u53d1\u751f\u6025\u6027\u5fc3\u6897\u4e8b\u4ef6\u53d1\u751f\uff0c\u6216\u5bfc\u81f4\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<sup>[2-4]<\/sup>\u3002\u7537\u6027\u53d1\u751f\u5fc3\u6e90\u6027\u731d\u6b7b\u7684\u98ce\u9669\u9ad8\u4e8e\u5973\u6027\uff0c\u8fd9\u4e0e\u7537\u6027\u548c\u5973\u6027\u4f53\u5185\u7684\u6027\u6fc0\u7d20\u6c34\u5e73\u76f8\u5173\u3002\u5973\u6027\u4f53\u5185\u8f83\u9ad8\u7684\u96cc\u6fc0\u7d20\u6c34\u5e73\u5177\u6709\u4e00\u5b9a\u7684\u5fc3\u8111\u8840\u7ba1\u4fdd\u62a4\u4f5c\u7528\u3002\u53e6\u5916\uff0c\u7537\u6027\u7684\u751f\u6d3b\u538b\u529b\u548c\u60c5\u7eea\u6ce2\u52a8\u8f83\u5927\uff0c\u5438\u70df\u3001\u9157\u9152\u7684\u6bd4\u4f8b\u4e5f\u66f4\u9ad8\uff0c\u8fd9\u4e9b\u90fd\u662f\u5bfc\u81f4\u7537\u6027\u731d\u6b7b\u98ce\u9669\u9ad8\u4e8e\u5973\u6027\u7684\u539f\u56e0\u3002\u901a\u5e38\u5973\u6027\u5fc3\u810f\u4e8b\u4ef6\u7684\u53d1\u751f\u5e74\u9f84\u665a\u4e8e\u7537\u602710~20\u5e74\uff0c\u4f46\u5728\u7ecf\u7edd\u671f\u540e\uff0c\u5973\u6027\u5fc3\u810f\u4e8b\u4ef6\u7684\u53d1\u751f\u7387\u4e5f\u4f1a\u9010\u6b65\u5347\u9ad8\u3002\u9ad8\u8840\u538b\u3001\u9ad8\u8102\u8840\u75c7\u3001\u9ad8\u8840\u7cd6\u7b49\u662f\u51a0\u72b6\u52a8\u8109\u7ca5\u6837\u786c\u5316\u7684\u91cd\u8981\u5371\u9669\u56e0\u7d20\uff0c\u4ee5\u4e0a\u5371\u9669\u56e0\u7d20\u63a7\u5236\u4e0d\u597d\u7684\u60a3\u8005\u5f80\u5f80\u731d\u6b7b\u98ce\u9669\u66f4\u9ad8\u3002<\/p><p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u8fd8\u6709\u5c31\u662f\u4e0d\u9002\u5b9c\u9ad8\u5f3a\u5ea6\u8fd0\u52a8\u7684\u4eba\u7fa4\uff0c\u9700\u8981\u901a\u8fc7\u57fa\u56e0\u68c0\u6d4b\u5145\u5206\u4e86\u89e3\u81ea\u8eab\u7684\u9057\u4f20\u98ce\u9669\uff08Genetic Risk\uff09\u3002\u4e00\u4e9b\u4f20\u7edf\u89c2\u70b9\u8ba4\u4e3a\uff0c\u4f53\u80b2\u953b\u70bc\u5bf9\u5fc3\u810f\u5065\u5eb7\u6709\u76ca\uff0c\u6709\u52a9\u4e8e\u964d\u4f4e\u5fc3\u8840\u7ba1\u75be\u75c5\u53d1\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u3002\u7136\u800c\uff0c\u8fd1\u5e74\u7814\u7a76\u8868\u660e\u8fc7\u5ea6\u8fd0\u52a8\u53ef\u80fd\u5bf9\u5fc3\u810f\u4ea7\u751f\u4e0d\u5229\u5f71\u54cd\u3002\u300aNEJM Evid\u300b\u53d1\u8868\u7684\u4e00\u7bc7\u7efc\u8ff0\u63d0\u793a\u5267\u70c8\u8010\u529b\u8fd0\u52a8\u589e\u52a0\u5fc3\u808c\u7ec6\u80de\u635f\u4f24\u6807\u5fd7\u7269\uff0c\u6307\u51fa\u7ec8\u8eab\u8010\u529b\u8fd0\u52a8\u53ef\u80fd\u589e\u52a0\u5fc3\u808c\u7622\u75d5\u3001\u51a0\u72b6\u52a8\u8109\u7ca5\u6837\u786c\u5316\u3001\u623f\u98a4\u548c\u4e3b\u52a8\u8109\u6269\u5f20\u7b49\u75be\u75c5\u98ce\u9669<sup>[5]<\/sup>\u3002<\/p><p>\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a2ed205 elementor-widget elementor-widget-text-editor\" data-id=\"a2ed205\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>\u731d\u6b7b\u524d\u6709\u54ea\u4e9b\u5f81\u5146\uff1f<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-457b3d6 elementor-widget elementor-widget-text-editor\" data-id=\"457b3d6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0 \u731d\u6b7b\u5f80\u5f80\u6765\u5f97\u975e\u5e38\u7a81\u7136\uff0c\u8d85\u8fc7\u4e00\u534a\u7684\u4eba\u5728\u731d\u6b7b\u53d1\u751f\u524d\u51e0\u4e4e\u6ca1\u6709\u4efb\u4f55\u7279\u5f02\u6027\u5f81\u5146\u3002\u4f46\u731d\u6b7b\u5e76\u975e\u5b8c\u5168\u65e0\u8ff9\u53ef\u5bfb\uff0c\u4e00\u90e8\u5206\u4eba\u5728\u731d\u6b7b\u524d\u4f1a\u51fa\u73b0\u5fc3\u60b8\u3001\u80f8\u75db\u3001\u547c\u5438\u6025\u4fc3\u3001\u5934\u6655\u3001\u4e4f\u529b\u7b49\u8868\u73b0\u3002\u5728\u4eba\u7fa4\u4e2d\uff0c\u51a0\u5fc3\u75c5\u4e0e\u8111\u5352\u4e2d\u9057\u4f20\u98ce\u9669\uff08Genetic Risk\uff09\u9ad8\u7684\uff0c\u66f4\u9700\u8981\u5173\u6ce8\u81ea\u8eab\u751f\u7406\u751f\u5316\u6307\u6807\u7684\u5f02\u5e38\u3002\u5b58\u5728\u731d\u6b7b\u9ad8\u5371\u56e0\u7d20\u7684\u4eba\u5982\u679c\u51fa\u73b0\u4ee5\u4e0b\u5f81\u5146\uff0c\u9700\u8981\u9ad8\u5ea6\u8b66\u60d5\uff0c\u5efa\u8bae\u65e9\u671f\u7cbe\u51c6\u7b5b\u67e5\uff0c\u51fa\u73b0\u86db\u4e1d\u9a6c\u8ff9\u7684\u75c7\u72b6\u65f6\u5019<strong>\u53ca\u65f6\u5c31\u533b\uff0c\u5fc5\u8981\u65f6\u8fdb\u884c\u836f\u7269\u6216\u624b\u672f\u6cbb\u7597<\/strong>\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b9c8d66 elementor-widget elementor-widget-image\" data-id=\"b9c8d66\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"580\" height=\"323\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20250402164748-1024x570.png\" class=\"attachment-large size-large wp-image-1010\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20250402164748-1024x570.png 1024w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20250402164748-300x167.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20250402164748-768x427.png 768w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20250402164748-1200x668.png 1200w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20250402164748.png 1280w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-35143c4 elementor-widget elementor-widget-text-editor\" data-id=\"35143c4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #993300;\"><strong>\u5f81\u51461\uff1a\u80f8\u95f7<\/strong><\/span><\/p>\n<p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u5982\u679c\u8fd1\u671f\u7a81\u7136\u51fa\u73b0\u6d3b\u52a8\u540e\u80f8\u95f7\u4e14\u4f11\u606f\u4e00\u6bb5\u65f6\u95f4\u540e\u7f13\u89e3\uff0c\u5f80\u5f80\u9884\u793a\u7740\u53ef\u80fd\u7f79\u60a3\u51a0\u5fc3\u75c5\u3002\u7a81\u7136\u51fa\u73b0\u7684\u75c7\u72b6\u8868\u660e\u51a0\u72b6\u52a8\u8109\u5185\u7684\u7ca5\u6837\u786c\u5316\u6591\u5757\u5e76\u4e0d\u7a33\u5b9a\uff0c\u968f\u65f6\u6709\u53ef\u80fd\u7834\u88c2\u800c\u5f62\u6210\u8840\u6813\uff0c\u9020\u6210\u51a0\u72b6\u52a8\u8109\u7ba1\u8154\u72ed\u7a84\u52a0\u91cd\u751a\u81f3\u95ed\u585e\uff0c\u5bfc\u81f4\u5fc3\u808c\u6897\u6b7b\u3002\u5982\u679c\u4ee5\u524d\u5076\u6709\u80f8\u95f7\u75c7\u72b6\uff0c\u8fd1\u671f\u80f8\u95f7\u53d1\u4f5c\u66f4\u52a0\u9891\u7e41\uff0c\u7a0b\u5ea6\u66f4\u52a0\u4e25\u91cd\uff0c\u540c\u6837\u63d0\u793a\u4ee5\u524d\u5c1a\u5c5e\u7a33\u5b9a\u7684\u6591\u5757\u76ee\u524d\u51fa\u73b0\u4e86\u5c0f\u7834\u88c2\uff0c\u5e76\u4e14\u968f\u65f6\u6709\u53ef\u80fd\u53d1\u5c55\u4e3a\u66f4\u5927\u7684\u7834\u88c2\uff0c\u5bfc\u81f4\u6025\u6027\u5fc3\u808c\u6897\u6b7b\u3002<\/p>\n<p><span style=\"color: #993300;\"><strong>\u5f81\u51462\uff1a\u5fc3\u614c<\/strong><\/span><\/p>\n<p>\u00a0 \u00a0 \u00a0 \u00a0 \u5fc3\u614c\u5f80\u5f80\u662f\u5fc3\u7387\u52a0\u5feb\u7684\u4e3b\u89c2\u611f\u53d7\uff0c\u4e0d\u5b9a\u671f\u51fa\u73b0\u5fc3\u7387\u52a0\u5feb\u901a\u5e38\u662f\u5feb\u901f\u6027\u5fc3\u5f8b\u5931\u5e38\u7684\u7ed3\u679c\u3002\u5927\u591a\u6570\u5fc3\u5f8b\u5931\u5e38\u7684\u5371\u9669\u6027\u8f83\u5c0f\uff0c\u4e00\u822c\u4e0d\u4f1a\u5f15\u53d1\u731d\u6b7b\uff0c\u4f46\u5982\u679c\u662f\u9891\u7e41\u53d1\u4f5c\u7684\u5ba4\u6027\u5fc3\u5f8b\u5931\u5e38\uff0c\u5219\u6709\u53d1\u5c55\u4e3a\u5fc3\u5ba4\u98a4\u52a8\uff08\u76f8\u5f53\u4e8e\u5fc3\u640f\u9aa4\u505c\uff09\u7684\u98ce\u9669\u3002\u53e6\u5916\uff0c\u5f88\u591a\u8001\u5e74\u4eba\u51fa\u73b0\u5fc3\u614c\u7684\u539f\u56e0\u662f\u5fc3\u623f\u98a4\u52a8\uff08\u4e00\u79cd\u5fc3\u8df3\u5feb\u6162\u4e0d\u4e00\u7684\u5fc3\u5f8b\u5931\u5e38\uff09\uff0c\u5982\u679c\u5fc3\u623f\u98a4\u52a8\u4f34\u53d1\u5fc3\u810f\u4f20\u5bfc\u5f02\u5e38\uff0c\u4e5f\u5f88\u5bb9\u6613\u8fdb\u5c55\u4e3a\u5fc3\u5ba4\u98a4\u52a8\u3002\u5fc3\u5ba4\u98a4\u52a8\u53d1\u4f5c\u540e\uff0c\u6570\u5206\u949f\u5185\u5373\u53ef\u5bfc\u81f4\u60a3\u8005\u6b7b\u4ea1\u3002\u56e0\u6b64\uff0c\u9891\u7e41\u5fc3\u614c\u53d1\u4f5c\u5e94\u53ca\u65f6\u5c31\u8bca\u3002<\/p>\n<p><span style=\"color: #993300;\"><strong>\u5f81\u51463\uff1a\u80a2\u4f53\u9ebb\u6728\u6216\u762b\u75ea<\/strong><\/span><\/p>\n<p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u8111\u5352\u4e2d\uff0c\u5c24\u5176\u662f\u51fa\u8840\u6027\u8111\u5352\u4e2d\uff0c\u662f\u5f15\u8d77\u731d\u6b7b\u7684\u91cd\u8981\u75c5\u56e0\u3002\u90e8\u5206\u8111\u5352\u4e2d\u8d77\u75c5\u6025\u9aa4\uff0c\u51e0\u5206\u949f\u5185\u60a3\u8005\u5c31\u4f1a\u53d1\u751f\u8840\u538b\u589e\u9ad8\u3001\u80a2\u4f53\u762b\u75ea\uff0c\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\u82e5\u80fd\u53ca\u65f6\u9001\u533b\uff0c\u60a3\u8005\u88ab\u6210\u529f\u6551\u6cbb\u7684\u53ef\u80fd\u6027\u8f83\u5927\u3002\u90e8\u5206\u8111\u5352\u4e2d\u8d77\u75c5\u7f13\u6162\uff0c\u65e9\u671f\u53ea\u8868\u73b0\u4e3a\u8f7b\u5fae\u75c7\u72b6\uff0c\u60a3\u8005\u5f80\u5f80\u5e76\u4e0d\u5728\u610f\uff0c\u4e00\u65e6\u8fdb\u5c55\u5c31\u6709\u53ef\u80fd\u5f15\u53d1\u731d\u6b7b\uff0c\u56e0\u6b64\u9700\u8981\u591a\u52a0\u7559\u5fc3\u3002\u5c24\u5176\u662f\u65e2\u5f80\u60a3\u9ad8\u8840\u538b\u3001\u51a0\u5fc3\u75c5\u6216\u5fc3\u623f\u98a4\u52a8\u7684\u60a3\u8005\uff0c\u8111\u5352\u4e2d\u7684\u53d1\u751f\u7387\u672c\u5c31\u9ad8\u4e8e\u666e\u901a\u4eba\u7fa4\uff0c\u5982\u679c\u51fa\u73b0\u5355\u4fa7\u773c\u775b\u89c6\u7269\u4e0d\u6e05\u3001\u5355\u4fa7\u80a2\u4f53\u9ebb\u6728\u3001\u4e4f\u529b\u6216\u6b65\u6001\u4e0d\u7a33\u3001\u6709\u8e29\u68c9\u82b1\u611f\uff0c\u5e94\u8b66\u60d5\u8111\u5352\u4e2d\u3002<\/p>\n<p><span style=\"color: #993300;\"><strong>\u5f81\u51464\uff1a\u547c\u5438\u56f0\u96be\uff0c\u5927\u91cf\u51fa\u6c57<\/strong><\/span><\/p>\n<p>\u00a0 \u00a0 \u00a0 \u00a0 \u5ffd\u7136\u5267\u70c8\u54b3\u55fd\u3001\u547c\u5438\u56f0\u96be\u3001\u9762\u8272\u7531\u7ea2\u6da6\u8f6c\u4e3a\u9752\u7d2b\u3001\u70e6\u8e81\u4e0d\u5b89\u7b49\uff0c\u53ef\u80fd\u662f\u5f02\u7269\u963b\u585e\u6c14\u9053\u3001\u5589\u5934\u6c34\u80bf\u7b49\u5bfc\u81f4\u7684\u6c14\u4f53\u4ea4\u6362\u969c\u788d\uff0c\u8868\u73b0\u4e3a\u8eab\u4f53\u7f3a\u6c27\u3002\u5728\u5fc3\u6e90\u6027\u731d\u6b7b\u53d1\u4f5c\u524d\uff0c\u4eba\u4f53\u5f80\u5f80\u4f1a\u51fa\u5927\u91cf\u51b7\u6c57\uff0c\u5168\u8eab\u76ae\u80a4\u6e7f\u51b7\u4e0d\u582a\uff0c\u8fd9\u662f\u5fc3\u808c\u6897\u6b7b\u53d1\u4f5c\u7684\u5178\u578b\u8868\u73b0\u4e4b\u4e00\u3002\u5982\u679c\u65e2\u5f80\u65e0\u5fc3\u810f\u75c5\u53f2\uff0c\u4f46\u7a81\u7136\u51fa\u73b0\u4e4f\u529b\u3001\u5927\u6c57\u6dcb\u6f13\u3001\u5fc3\u524d\u533a\u4e0d\u9002\uff0c\u751a\u81f3\u80f8\u80cc\u75bc\u75db\u7b49\u75c7\u72b6\uff0c\u5207\u52ff\u9ebb\u75f9\u5927\u610f\uff0c\u4e00\u5b9a\u8981\u4e86\u89e3\u8fd9\u662f\u8eab\u4f53\u5728\u53d1\u51fa\u7684\u4e25\u91cd\u201c\u8b66\u544a\u201d\u3002<\/p>\n<p><span style=\"color: #993300;\"><strong>\u5f81\u51465\uff1a\u5176\u4ed6\u5f02\u5e38\u8868\u73b0<\/strong><\/span><\/p>\n<p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u5e73\u7d20\u8840\u538b\u63a7\u5236\u4e0d\u4f73\u7684\u60a3\u8005\u5982\u679c\u7a81\u7136\u51fa\u73b0\u5267\u70c8\u5934\u75db\uff0c\u751a\u81f3\u4f34\u6709\u5455\u5410\uff0c\u5e94\u9ad8\u5ea6\u6000\u7591\u53d1\u751f\u4e86\u8111\u8840\u7ba1\u610f\u5916\uff0c\u6709\u53ef\u80fd\u5f15\u53d1\u731d\u6b7b\uff1b\u7a81\u7136\u660f\u8ff7\u53ef\u80fd\u7531\u591a\u79cd\u75be\u75c5\u6240\u81f4\uff0c\u5176\u4e2d\u90e8\u5206\u75c5\u56e0\u4ea6\u53ef\u5f15\u53d1\u731d\u6b7b\u3002<\/p>\n<p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u603b\u4e4b\uff0c\u53ca\u65f6\u53d1\u73b0\u731d\u6b7b\u7684\u5f81\u5146\uff0c\u9700\u8981\u6211\u4eec\u5bf9\u8eab\u4f53\u7684\u5404\u79cd\u4e0d\u9002\u65f6\u523b\u4fdd\u6301\u8b66\u60d5\uff0c\u5982\u5f88\u591a\u4eba\u8ba4\u4e3a\u5fc3\u808c\u6897\u6b7b\u7684\u8868\u73b0\u4e3a\u80f8\u75db\uff0c\u4f46\u90e8\u5206\u60a3\u8005\u5374\u8868\u73b0\u4e3a\u5de6\u4fa7\u80cc\u75db\u3001\u80a9\u8180\u75db\u751a\u81f3\u624b\u81c2\u75db\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a43b70b elementor-widget elementor-widget-text-editor\" data-id=\"a43b70b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0 \u4e2d\u56fd\u5fc3\u6e90\u6027\u731d\u6b7b\u7684\u4eba\u6570\u6bcf\u5e74\u7ea6<strong>55\u4e07<\/strong>\uff0c\u6bcf\u65e5<strong>\u81f3\u5c111500<\/strong>\u4eba\u5fc3\u810f\u9aa4\u505c\uff0c\u4f4d\u5c45\u5168\u7403\u4e4b\u51a0\u3002\u4f46\u5176\u4e2d<strong>\u4e0d\u8db31%<\/strong>\u7684\u4eba\u6210\u529f\u7684\u83b7\u6551\u3002\u56e0\u6b64\uff0c\u8d85\u65e9\u671f\u7684\u9884\u8b66\u5c24\u4e3a\u91cd\u8981\uff1b\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u662f\u4e00\u79cd\u590d\u6742\u75be\u75c5\uff0c\u5fc3\u6e90\u6027\u731d\u6b7b\u662f\u5f88\u96be\u901a\u8fc7\u5e38\u89c4\u65b9\u6cd5\u68c0\u6d4b\u53d1\u73b0\u7684\uff0c50%\u7684\u75c5\u4f8b\u6ca1\u6709\u4e34\u5e8a\u8868\u73b0\uff0c\u5b58\u5728\u65e0\u75c7\u72b6\u6216\u75c7\u72b6\u8f7b\u5fae\u7684\u60c5\u51b5\uff0c\u9996\u53d1\u75c7\u72b6\u5c31\u662f\u731d\u6b7b\u3002\u5e38\u89c4\u7684\u68c0\u6d4b\u65b9\u6cd5\uff0c\u5982\u542c\u8bca\u3001\u5fc3\u7535\u56fe\u3001\u5fc3\u8840\u7ba1\u9020\u5f71\u3001CT\u68c0\u67e5\u7b49\uff0c\u53ef\u4ee5\u8d77\u5230\u4e00\u5b9a\u7684\u5e2e\u52a9\u4f5c\u7528\uff0c\u4f46\u662f\u5bf9\u4e8e\u4e00\u4e9b\u8ddf\u731d\u6b7b\u76f8\u5173\u7684\u9690\u533f\u6027\u75be\u75c5\uff0c\u5982QT\u7efc\u5408\u5f81\u3001\u51a0\u5fc3\u75c5\uff0c\u51a0\u72b6\u52a8\u8109\u72ed\u7a84\u7a0b\u5ea6\u5c0f\u4e8e50%\u7684\u75c5\u75c7\uff0c\u5b8c\u5168\u65e0\u80fd\u4e3a\u529b\u3002\u800c\u4e14\uff0c\u7ea670%\u7684\u5fc3\u6e90\u6027\u731d\u6b7b\u4e0d\u9002\u7528\u4e8e\u9664\u98a4\u5668\u6cbb\u7597\u3002<\/p><p>\u00a0 \u00a0 \u00a0 \u00a0 \u65e9\u671f\u8bca\u65ad\u548c\u6cbb\u7597\u5bf9\u4e8e\u9884\u9632\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u81f3\u5173\u91cd\u8981\u3002\u4ece\u57fa\u56e0\u5c42\u9762\u8bc4\u4f30\u731d\u6b7b\u98ce\u9669\u5bf9\u4e8e\u9884\u9632\u731d\u6b7b\u81f3\u5173\u91cd\u8981\uff0c\u4ece\u591a\u57fa\u56e0\u4e0e\u5355\u57fa\u56e0\u7684\u68c0\u6d4b\u5168\u9762\u8bc4\u4f30\u5fc3\u8111\u8840\u7ba1\u75c5\u7684\u9057\u4f20\u98ce\u9669\uff08Genetic Risk\uff09\uff0c\u9884\u77e5\u98ce\u9669\u6982\u7387\u540e\uff0c\u901a\u8fc7\u5b9e\u65bd\u9884\u9632\u6027\u89e3\u51b3\u65b9\u6848\uff0c\u80fd\u591f\u6709\u6548\u964d\u4f4e\u731d\u6b7b\u7684\u53d1\u751f\u6982\u7387\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8933b74 elementor-widget elementor-widget-text-editor\" data-id=\"8933b74\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>\u7cbe\u51c6\u7b5b\u67e5<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-65bec1a elementor-widget elementor-widget-text-editor\" data-id=\"65bec1a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;\u5fc3\u8111\u8840\u7ba1\u5065\u5eb7\u8bc4\u4f30\u82af\u7247\uff08 \u6653\u82af\u7518<sup>TM<\/sup>\uff09\uff0c\u6db5\u76d6\u4e86<strong>528<\/strong>\u4e2a\u57fa\u56e0\uff0c<strong>661<\/strong>\u4e2a\u5355\u6838\u82f7\u9178\u591a\u6001\u6027\u4f4d\u70b9\uff08PRS\uff09\uff0c<strong>27<\/strong>\u4e2a\u836f\u7269\u57fa\u56e0\u4ee3\u8c22\u4f4d\u70b9\uff1b\u5176\u4e2d\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u4f30\u68c0\u6d4b\u5305\u62ec\u51a0\u5fc3\u75c5\u4e0e\u8111\u5352\u4e2d\uff0c\u5355\u57fa\u56e0\u68c0\u6d4b\u6db5\u76d68\u5927\u7c7b\u5fc3\u8840\u7ba1\u75be\u75c5\uff0c\u5982\u5fc3\u808c\u75c5\u3001\u5fc3\u810f\u79bb\u5b50\u901a\u9053\u75c5\uff08\u5305\u62ecQT\u7efc\u5408\u5f81\uff09\u3001\u5355\u57fa\u56e0\u9057\u4f20\u6027\u9ad8\u8840\u538b\u3001\u9057\u4f20\u6027\u4e3b\u52a8\u8109\u75be\u75c5\u3001\u80ba\u52a8\u8109\u9ad8\u538b\u3001\u9057\u4f20\u6027\u6613\u6813\u75c7\u3001\u5bb6\u65cf\u6027\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u3001\u5355\u57fa\u56e0\u9057\u4f20\u6027\u8111\u5c0f\u8840\u7ba1\u3002<\/p>\n<p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;\u6653\u82af\u7518<sup>TM<\/sup>\u68c0\u6d4b\u4ee5\u591a\u57fa\u56e0\u9057\u4f20\u98ce\u9669\u4e3a\u57fa\u7840\uff0c\u52a0\u4e0a\u5355\u57fa\u56e0\u81f4\u75c5\u4f4d\u70b9\u7684\u68c0\u6d4b\uff0c\u53ef\u4ee5\u5168\u9762\u8bc4\u4f30\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u7684\u9057\u4f20\u98ce\u9669\uff08Genetic Risk\uff09\uff0c\u5b9e\u73b0\u7cbe\u51c6\u7b5b\u67e5\uff1b\u5229\u7528\u591a\u57fa\u56e0\u9057\u4f20\u98ce\u9669\u548c\u4e34\u5e8a\u98ce\u9669\u7684\u7efc\u5408\u6a21\u578b\u80fd\u591f\u66f4\u52a0\u7cbe\u7ec6\u5316\u7684\u8fdb\u884c\u98ce\u9669\u5206\u5c42\uff1b\u7ed3\u5408\u836f\u7269\u57fa\u56e0\u4ee3\u8c22\u7684\u68c0\u6d4b\uff0c\u9488\u5bf9\u9ad8\u98ce\u9669\u4eba\u7fa4\u8fdb\u884c\u4e2a\u6027\u5316\u5e72\u9884\u4ee5\u53ca\u6709\u6548\u6cbb\u7597\u3002<\/p>\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u6653\u82af\u7518<sup>TM<\/sup>\u68c0\u6d4b\u5e94\u7528\u7684\u7814\u53d1\u4e0e\u8f6c\u5316\u662f\u57fa\u4e8e\u8fc7\u53bb\u4e8c\u5341\u5e74\u987e\u4e1c\u98ce\u9662\u58eb\u5e26\u9886\u7684\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e2d\u5fc3\u7814\u7a76\u56e2\u961f\u7684\u4e2d\u56fd\u4eba\u7fa4\u5927\u961f\u5217\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\uff0c\u8fd1\u5341\u591a\u5e74\u7814\u7a76\u56e2\u961f\u534f\u8c03\u7ec4\u7ec7\u4e86\u4e2d\u56fd\u3001\u65b0\u52a0\u5761\u3001\u9a6c\u6765\u897f\u4e9a\u3001\u65e5\u672c\u3001\u83f2\u5f8b\u5bbe\u7b49\u4e1c\u4e9a\u4eba\u7fa4\u4ee5\u53ca\u6b27\u7f8e\u4eba\u7fa4\uff0c\u6d89\u53ca\u5230\u5168\u7403\u8fd1100\u4f59\u4e2a\u961f\u5217\uff0c\u5f00\u5c55\u4e86\u5927\u961f\u5217\u4e2d\u56fd\u4eba\u7fa4\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\uff0c\u7cfb\u7edf\u5730\u89e3\u7801\u4e86\u5f71\u54cd\u4e2d\u56fd\u4eba\u7fa4\u51a0\u5fc3\u75c5\u3001\u8111\u5352\u4e2d\u4ee5\u53ca\u8840\u8102\u5f02\u5e38\u3001\u9ad8\u8840\u538b\u7b49\u4e3b\u8981\u5371\u9669\u56e0\u7d20\u7684\u9057\u4f20\u4fe1\u606f\uff0c\u76f8\u5173\u7814\u7a76\u6210\u679c\u53d1\u8868\u5728Nature Genetics\u3001European Heart Journal\u7b49\u4e16\u754c\u9876\u5c16\u7684\u5b66\u672f\u671f\u520a\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-069289a elementor-widget elementor-widget-text-editor\" data-id=\"069289a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #808080;\">\u53c2\u8003\u8d44\u6599<\/span><\/p><p><span style=\"color: #808080;\">[1] \u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e2d\u5fc3\u5fc3\u808c\u75c5\u4e13\u79d1\u8054\u76df. \u4e2d\u56fd\u6210\u4eba\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u8bca\u65ad\u4e0e\u6cbb\u7597\u6307\u53572023[J]. \u4e2d\u56fd\u5faa\u73af\u6742\u5fd7, 2023, 38: 1-33.<\/span><\/p><p><span style=\"color: #808080;\">[2]\u300a\u4e2d\u56fd\u5fc3\u8840\u7ba1\u75c5\u98ce\u9669\u8bc4\u4f30\u548c\u7ba1\u7406\u6307\u5357\u300b<\/span><\/p><p><span style=\"color: #808080;\">[3] Lu X, Liu Z, Cui Q, et al. A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J. 2022;43(18):1702-1711.<\/span><\/p><p><span style=\"color: #808080;\">[4] Lu X, Niu X, Shen C, et al. Development and Validation of a Polygenic Risk Score for Stroke in the Chinese Population. Neurology. 2021;97(6):e619-e628.<\/span><\/p><p><span style=\"color: #808080;\">[5] Thompson PD, Eijsvogels TMH, Kim JH. Can the heart get an overuse sports injury? NEJM Evid 2023;2:EVIDra2200175.<\/span><\/p><p><span style=\"color: #808080;\">[6] Akhtar M M , Lorenzini M , Cicerchia M ,et al.Clinical Phenotypes and Prognosis of Dilated Cardiomyopathy Caused by Truncating Variants in the TTN Gene[J].Circulation Heart Failure, 2020, 13(10):CIRCHEARTFAILURE119006832.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u9884\u9632\u731d\u6b7b \u4ec0\u4e48\u662f\u731d\u6b7b\uff1f \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u731d\u6b7b\u5c31\u662f\u5e73\u65f6\u8eab\u4f53\u5065\u5eb7\u3001\u6216\u8c8c\u4f3c\u5065\u5eb7\u7684\u4eba\uff0c\u5728\u975e\u5e38\u77ed\u7684\u65f6\u95f4\u5185\uff0c\u56e0\u81ea\u7136\u75be\u75c5\u800c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1015,"comment_status":"closed","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-1008","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts\/1008","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1008"}],"version-history":[{"count":53,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts\/1008\/revisions"}],"predecessor-version":[{"id":1803,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts\/1008\/revisions\/1803"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/media\/1015"}],"wp:attachment":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1008"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1008"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1008"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}