{"id":1205,"date":"2025-04-03T14:06:02","date_gmt":"2025-04-03T06:06:02","guid":{"rendered":"https:\/\/cvd.xin\/?p=1205"},"modified":"2025-04-07T17:08:35","modified_gmt":"2025-04-07T09:08:35","slug":"%e6%97%a9%e9%98%b2%e3%80%81%e6%97%a9%e6%b2%bb-%e5%86%a0%e5%bf%83%e7%97%85%e5%a4%9a%e5%9f%ba%e5%9b%a0%e9%a3%8e%e9%99%a9%e8%af%84%e4%bc%b0%e6%8c%87%e5%af%bc%e9%9d%92%e5%b9%b4%e7%be%a4%e4%bd%93-2","status":"publish","type":"post","link":"https:\/\/cvd.xin\/?p=1205","title":{"rendered":"EHJ | \u5229\u7528\u7b80\u5355\u4e58\u6cd5\u6a21\u578b\uff0c\u5c06PRS\u4e0e\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u6a21\u578b\u7ed3\u5408\uff0c\u63d0\u5347\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u9884\u6d4b\u51c6\u786e\u6027"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1205\" class=\"elementor elementor-1205\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-480e822 e-flex e-con-boxed e-con e-parent\" data-id=\"480e822\" data-element_type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a00fa8d elementor-widget elementor-widget-heading\" data-id=\"a00fa8d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">EHJ | \u5229\u7528\u7b80\u5355\u4e58\u6cd5\u6a21\u578b\uff0c\u5c06PRS\u4e0e\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u6a21\u578b\u7ed3\u5408\uff0c\u63d0\u5347\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u9884\u6d4b\u51c6\u786e\u6027<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-618262f elementor-widget elementor-widget-post-info\" data-id=\"618262f\" data-element_type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-0263012 elementor-inline-item\" itemprop=\"author\">\n\t\t\t\t\t\t<a href=\"https:\/\/cvd.xin\/?author=1\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-user-circle\" viewBox=\"0 0 496 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M248 104c-53 0-96 43-96 96s43 96 96 96 96-43 96-96-43-96-96-96zm0 144c-26.5 0-48-21.5-48-48s21.5-48 48-48 48 21.5 48 48-21.5 48-48 48zm0-240C111 8 0 119 0 256s111 248 248 248 248-111 248-248S385 8 248 8zm0 448c-49.7 0-95.1-18.3-130.1-48.4 14.9-23 40.4-38.6 69.6-39.5 20.8 6.4 40.6 9.6 60.5 9.6s39.7-3.1 60.5-9.6c29.2 1 54.7 16.5 69.6 39.5-35 30.1-80.4 48.4-130.1 48.4zm162.7-84.1c-24.4-31.4-62.1-51.9-105.1-51.9-10.2 0-26 9.6-57.6 9.6-31.5 0-47.4-9.6-57.6-9.6-42.9 0-80.6 20.5-105.1 51.9C61.9 339.2 48 299.2 48 256c0-110.3 89.7-200 200-200s200 89.7 200 200c0 43.2-13.9 83.2-37.3 115.9z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-author\">\n\t\t\t\t\t\t\t\t\t\tcvd_xin\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-3567c0a elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/cvd.xin\/?m=20250403\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>2025-04-03<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ca1a1a5 elementor-widget elementor-widget-text-editor\" data-id=\"ca1a1a5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0 \u5bf9\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\uff08CVD\uff09\u98ce\u9669\u5177\u6709\u5fae\u5c0f\u5f71\u54cd\u7684\u5e38\u89c1\u57fa\u56e0\u53d8\u5f02\uff0c\u53ef\u7ec4\u5408\u6210\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206\uff08PRS\uff09\u3002\u7814\u7a76\u8868\u660e\uff0cPRS\u8bc4\u5206\u4e0e\u51a0\u5fc3\u75c5\uff08CAD\uff09\u6216\u8111\u5352\u4e2d\u7684\u60a3\u75c5\u7387\u76f8\u5173\u3002<strong>\u79d1\u5b66\u5bb6\u4e00\u76f4\u81f4\u529b\u4e8e\u5982\u4f55\u66f4\u597d\u5730\u5c06\u8fd9\u4e9b\u9057\u4f20\u4fe1\u606f\u6574\u5408\u5230\u4f20\u7edf\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u5de5\u5177\u4e2d\u3002<\/strong><\/p><p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a02022\u5e74\uff0c\u7531\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e2d\u5fc3\/\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u961c\u5916\u533b\u9662\u987e\u4e1c\u98ce\u9662\u58eb\u548c\u9c81\u5411\u950b\u6559\u6388\u9886\u8854\u7684\u7814\u7a76\u56e2\u961f\uff0c\u5728\u300a\u6b27\u6d32\u5fc3\u810f\u6742\u5fd7\u300b\uff08European Heart Journal\uff09\u53d1\u8868\u4e86\u4e2d\u56fd\u4eba\u7fa4\u7684\u9996\u4e2a\u51a0\u5fc3\u75c5\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206\u6a21\u578b\uff0c\u5e76\u57fa\u4e8e\u524d\u77bb\u6027\u961f\u5217\u53d1\u73b0\u5176\u80fd\u63d0\u5347\u4f20\u7edf\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u6a21\u578b\u7684\u518d\u5206\u5c42\u80fd\u529b\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-409c671 elementor-widget elementor-widget-image\" data-id=\"409c671\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"580\" height=\"365\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172703-1024x645.png\" class=\"attachment-large size-large wp-image-1206\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172703-1024x645.png 1024w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172703-300x189.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172703-768x484.png 768w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172703-1200x756.png 1200w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172703.png 1269w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-256ceff elementor-widget elementor-widget-text-editor\" data-id=\"256ceff\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>&nbsp; &nbsp; &nbsp; &nbsp; 2024\u5e74\uff0cLing Li<sup>[2]<\/sup>\u7b49\u4eba\u63d0\u51fa\u4e86\u4e00\u5957\u57fa\u4e8e\u7b80\u5355\u7684\u4e58\u6cd5\u6a21\u578b \u201cSCORE2 \u00d7 PRS \u56e0\u5b50\u201d\u7684\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u98ce\u9669\u9884\u6d4b\u6a21\u578b\uff0cSCORE2\u662f\u6b27\u6d32\u5fc3\u810f\u75c5\u5b66\u4f1a (ESC) \u63a8\u8350\u7684\u4e34\u5e8a\u98ce\u9669\u8bc4\u5206\u5de5\u5177\uff0c\u8be5\u6a21\u578b\u53ef\u4ee5\u6539\u5584\u4f20\u7edf\u4e34\u5e8a\u98ce\u9669\u8bc4\u5206\u7684\u51c6\u786e\u6027\uff0c\u76f8\u5173\u7814\u7a76\u53d1\u8868\u5728\u300a\u6b27\u6d32\u5fc3\u810f\u6742\u5fd7\u300b\uff08European Heart Journal\uff09\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-43d62fa elementor-widget elementor-widget-image\" data-id=\"43d62fa\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"580\" height=\"301\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172739.png\" class=\"attachment-large size-large wp-image-1207\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172739.png 967w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172739-300x156.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172739-768x399.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c9a7f6c elementor-widget elementor-widget-text-editor\" data-id=\"c9a7f6c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><strong><span style=\"color: #000080;\">\u65b9\u6cd5<\/span><\/strong><\/p>\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u5728\u82f1\u56fd\u751f\u7269\u5e93 (n = 432981) \u7684\u53c2\u4e0e\u8005\u4e2d\u8ba1\u7b97\u4e86\u51a0\u72b6\u52a8\u8109\u75be\u75c5 (CAD) \u7684PRS\u3002\u5728 PRS \u5206\u5e03\u7684\u6bcf\u4e2a\u5341\u5206\u4f4d\u6570\u5185\uff0c\u5c06\u6574\u4e2a\u4eba\u7fa4\u4e0e\u4ee3\u8868\u4e34\u5e8a\u98ce\u9669\u8c31\u7684\u4e0d\u540c\u4e9a\u7ec4\u4e4b\u95f4\u7684\u5fc3\u8111\u8840\u7ba1\u75be\u75c5 (\u4f8b\u5982\u51a0\u5fc3\u75c5\u3001\u8111\u5352\u4e2d) \u7684\u4f18\u52bf\u6bd4 (Ors\uff0c\u79f0\u4e3a PRS \u56e0\u5b50)\u8fdb\u884c\u6bd4\u8f83\u3002\u5728\u5408\u5e76\u7684\u5f17\u96f7\u660e\u6c49\/\u793e\u533a\u52a8\u8109\u7ca5\u6837\u786c\u5316\u98ce\u9669 (ARIC) \u4eba\u7fa4 (n = 10 757) \u4e2d\u8fdb\u884c\u4e86\u9a8c\u8bc1\u3002\u901a\u8fc7\u98ce\u9669\u91cd\u65b0\u5206\u7c7b\u6d4b\u8bd5\u4e86\u4e58\u6cd5\u6a21\u578b\u201cSCORE2 \u00d7 PRS \u56e0\u5b50\u201d\u7684\u4e34\u5e8a\u9002\u7528\u6027\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e705bb8 elementor-widget elementor-widget-image\" data-id=\"e705bb8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"580\" height=\"253\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172749.png\" class=\"attachment-large size-large wp-image-1208\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172749.png 947w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172749-300x131.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172749-768x335.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1dd0331 elementor-widget elementor-widget-text-editor\" data-id=\"1dd0331\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #000080;\"><b>\u7ed3\u679c<\/b><\/span><\/p>\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u5728\u4e34\u5e8a\u98ce\u9669\u5dee\u5f02\u6781\u5927\u7684\u4e9a\u7ec4\u4e2d\uff0cCVD \u7684 OR \u5728\u6bcf\u4e2a PRS \u5341\u5206\u4f4d\u6570\u5185\u4fdd\u6301\u7a33\u5b9a\u3002SCORE2 \u548c PRS \u5728 CVD \u98ce\u9669\u65b9\u9762\u6ca1\u6709\u663e\u793a\u51fa\u663e\u7740\u7684\u4ea4\u4e92\u4f5c\u7528\uff0c\u5c06\u5b83\u4eec\u5b9a\u4e49\u4e3a\u4e58\u6cd5\u56e0\u5b50\uff1aSCORE2 \u00d7 PRS \u56e0\u5b50 = \u603b\u98ce\u9669\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9ed0527 elementor-widget elementor-widget-image\" data-id=\"9ed0527\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"355\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172756.png\" class=\"attachment-large size-large wp-image-1209\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172756.png 950w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172756-300x183.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172756-768x470.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2625b94 elementor-widget elementor-widget-image\" data-id=\"2625b94\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"313\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172805.png\" class=\"attachment-large size-large wp-image-1210\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172805.png 951w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172805-300x162.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172805-768x415.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0627df5 elementor-widget elementor-widget-image\" data-id=\"0627df5\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"351\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172812.png\" class=\"attachment-large size-large wp-image-1211\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172812.png 950w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172812-300x182.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172812-768x465.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-98dc2d9 elementor-widget elementor-widget-text-editor\" data-id=\"98dc2d9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u5728\u82f1\u56fd\u751f\u7269\u5e93\u4e2d\uff0c\u4e58\u6cd5\u6a21\u578b\u5c06\u4e2d\u98ce\u9669\u7ec4 (n = 145 337) \u7684 <strong>9.55% <\/strong>\u79fb\u81f3<strong>\u9ad8\u98ce\u9669\u7ec4<\/strong>\uff0c<strong>\u4f7f\u8be5\u7c7b\u522b\u7684\u4e2a\u4f53\u589e\u52a0\u4e8656.6%<\/strong>\u3002\u901a\u8fc7 PRS \u56e0\u5b50\u4ece\u4e2d\u98ce\u9669\u91cd\u65b0\u5206\u7c7b\u5230\u9ad8\u98ce\u9669\u7684\u4e2a\u4f53\u4e2d\uff0c\u53d1\u751f\u4e8b\u4ef6\u6027 CVD \u7684\u6bd4\u4f8b\u4e3a8.08%\uff0c\u5927\u7ea6\u662f\u90a3\u4e9b\u4ecd\u7136\u5904\u4e8e\u4e2d\u95f4\u98ce\u9669\u7684\u4e2a\u4f53 (4.08%) \u76842\u500d\u3002\u540c\u6837\uff0cPRS \u56e0\u5b50\u5728\u5f17\u96f7\u660e\u6c49\/ARIC \u4e2d\u5c06 8.29% \u7684\u4e2a\u4f53\u4ece\u4e2d\u98ce\u9669\u79fb\u81f3\u9ad8\u98ce\u9669\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dbebea6 elementor-widget elementor-widget-image\" data-id=\"dbebea6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"358\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172938.png\" class=\"attachment-large size-large wp-image-1212\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172938.png 950w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172938-300x185.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172938-768x474.png 768w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-32fc526 elementor-widget elementor-widget-text-editor\" data-id=\"32fc526\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #000080;\"><strong>\u7ed3\u8bba\u548c\u610f\u4e49<\/strong><\/span><\/p>\n<p>&nbsp; &nbsp; &nbsp; &nbsp; \u672c\u7814\u7a76\u8868\u660e\uff0c\u7531\u4e34\u5e8a\u98ce\u9669\u8bc4\u5206\u786e\u5b9a\u7684\u7edd\u5bf9 CVD \u98ce\u9669\u548c\u7531 PRS \u786e\u5b9a\u7684\u76f8\u5bf9\u9057\u4f20\u98ce\u9669\u63d0\u4f9b\u4e86\u72ec\u7acb\u7684\u4fe1\u606f\u3002\u8fd9\u4e24\u4e2a\u7ec4\u6210\u90e8\u5206\u53ef\u4ee5\u5f62\u6210\u4e00\u4e2a\u7b80\u5355\u7684\u4e58\u6cd5\u6a21\u578b\uff0c\u4ece\u800c\u63d0\u9ad8\u4e34\u5e8a\u98ce\u9669\u6a21\u578b\u9884\u6d4bCVD \u7684\u7cbe\u786e\u6027\u3002\u8be5\u7b56\u7565\u663e\u8457\u63d0\u9ad8\u4e86\u9ad8\u5371\u53d7\u8bd5\u8005\u7684\u8bc6\u522b\u7387\uff0c\u4ece\u4e34\u5e8a\u89d2\u5ea6\u770b\uff0c\u5177\u6709\u5438\u5f15\u529b\u3002<\/p>\n<ul>\n<li><strong>\u5173\u952e\u53d1\u73b0<\/strong><\/li>\n<\/ul>\n<p><span style=\"letter-spacing: -0.27px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight ); font-size: 1.8rem;\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span>PRS \u663e\u793a\u7684\u4e2a\u4eba\u76f8\u5bf9\u9057\u4f20\u98ce\u9669\uff08\u7528\u4f18\u52bf\u6bd4\uff0c\u6216 PRS \u56e0\u5b50\u8868\u793a\uff09\u5728 PRS \u5206\u5e03\u7684\u6bcf\u4e2a\u5341\u5206\u4f4d\u4e0a\u90fd\u4fdd\u6301\u4e0d\u53d8\uff0c\u72ec\u7acb\u4e8e SCORE2 \u7684 10 \u5e74\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u7ed3\u679c\u3002\u201cSCORE2 x PRS \u56e0\u5b50\u201d\u4e58\u6cd5\u6a21\u578b\u5c06\u7ea6<strong> 10% \u7684\u4e2d\u5ea6\u98ce\u9669\u4eba\u7fa4\u63d0\u5347\u81f3\u9ad8\u98ce\u9669\u7ec4<\/strong>\u3002\u4f7f\u7528 PRS \u56e0\u5b50\u91cd\u65b0\u5206\u7c7b\u7684\u53d7\u8bd5\u8005\u60a3 CVD \u7684\u6bd4\u4f8b\u662f\u539f\u59cb\u4e2d\u5ea6\u98ce\u9669\u7ec4\u7684\u4e24\u500d\u3002<\/p>\n<ul>\n<li><strong>\u5173\u952e\u4fe1\u606f<\/strong><\/li>\n<\/ul>\n<p><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight ); font-size: 1.8rem; letter-spacing: -0.27px;\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight ); font-size: 1.8rem; letter-spacing: -0.27px;\">&nbsp;<\/span>PRS \u7684\u4f18\u52bf\u6bd4\u53ef\u4ee5\u7528\u4f5c\u4e58\u6570 (PRS \u56e0\u5b50)\uff0c\u4ece\u800c\u6539\u8fdb\u7edd\u5bf9\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u3002\u5c06\u4e34\u5e8a\u4f30\u8ba1\u98ce\u9669\u4e0e PRS \u56e0\u5b50\u76f8\u4e58\uff0c\u53ef\u63d0\u9ad8\u98ce\u9669\u9884\u6d4b\u7684\u7cbe\u786e\u6027\u3002PRS \u56e0\u5b50\u53ef\u5229\u7528\u9057\u4f20\u4fe1\u606f\uff0c\u63d0\u9ad8\u6307\u5357\u63a8\u8350\u7684\u9884\u6d4b\u5de5\u5177\u7684\u7cbe\u786e\u6027\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fd88f69 elementor-widget elementor-widget-image\" data-id=\"fd88f69\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"397\" src=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172946-1024x701.png\" class=\"attachment-large size-large wp-image-1213\" alt=\"\" srcset=\"https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172946-1024x701.png 1024w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172946-300x205.png 300w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172946-768x526.png 768w, https:\/\/cvd.xin\/wp-content\/uploads\/2025\/04\/\u5fae\u4fe1\u56fe\u7247_20241210172946.png 1069w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55090fe elementor-widget elementor-widget-text-editor\" data-id=\"55090fe\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #999999;\">\u53c2\u8003\u8d44\u6599<\/span><\/p><p><span style=\"color: #999999;\">1.Lu, X., et al., A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J, 2022.2. Li L , Pang S , Starnecker F ,et al.Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease[J].European Heart Journal: The Journal of the European Society of Cardiology, 2024(20):45.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>EHJ | \u5229\u7528\u7b80\u5355\u4e58\u6cd5\u6a21\u578b\uff0c\u5c06PRS\u4e0e\u4e34\u5e8a\u98ce\u9669\u8bc4\u4f30\u6a21\u578b\u7ed3\u5408\uff0c\u63d0\u5347\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u9884\u6d4b\u51c6\u786e\u6027 \u00a0 \u00a0 \u00a0 \u00a0 \u5bf9\u5fc3 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1217,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-1205","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts\/1205","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1205"}],"version-history":[{"count":43,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts\/1205\/revisions"}],"predecessor-version":[{"id":1787,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/posts\/1205\/revisions\/1787"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=\/wp\/v2\/media\/1217"}],"wp:attachment":[{"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1205"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1205"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cvd.xin\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}